Blood and Marrow Transplant Clinic

Epidermolysis Bullosa (EB)

Pediatric hematologists/oncologists from University of Minnesota Physicians provide groundbreaking treatment for epidermolysis bullosa (EB), a deficiency of one of several proteins that anchor the skin to the body, using a mixture of stem cells. These specialists are part of the Blood and Marrow Transplant (BMT) Program at University of Minnesota Amplatz Children’s Hospital, the only program in the world offering such treatment. This treatment, as well as others in development at the University of Minnesota, gives hope to patients and their families in dealing with this previously untreatable disease.


  • Pioneered the use of stem cells in the treatment of EB
  • Multidisciplinary care from specialists in dermatology, infectious disease, anesthesiology, pediatric surgery, gastroenterology, nephrology, nutrition, and pain management all experienced in EB
  • On-site specialty care is available including wound care, pain management, ophthalmologic care, orthopaedic care, G- tube replacement, physical and occupational therapy, speech and eating care, genetic counseling, and long-term follow up
  • World leaders in blood and marrow stem cell research and clinical care, continuing our legacy as home of the first successful bone marrow transplant in 1968
  • Highly experienced, having performed more than 5,500 blood and marrow stem cell transplants as of 2010



  • Opportunity for patients to participate in pioneering research studies and clinical trials
  • Committed to developing improved treatments for EB using different kinds of stem cells — including endeavors that aim to determine which types of stem cells are most effective for EB, new delivery methods such as injection into wounds, and more
  • Actively involved in collaborating with researchers around the world in exploring new and safer ways to treat EB and improve the quality of life for those with the disease
  • Exploring novel ways to increase cure rates and improve quality of life for patients with EB
  • Leading the nation in stem cell therapy for EB, including utilization of mesenchymal stem cells for tissue repair and use of the patient’s own skin to create genetically corrected stem cells, and translating that research into clinical practice



Central Scheduling: 612.672.7422

Provider Referrals: 612.672.7000

Administrative Offices: 612.884.0600

©2014 Regents of the University of Minnesota. All rights reserved.