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Glossary: hepatic veno-occlusive disease, Masonic Cancer Center, University of Minnesota

hepatic veno-occlusive disease

(heh-PA-tik VEE-noh-uh-KLOO-siv dih-ZEEZ)

A condition in which some of the veins in the liver are blocked. This causes a decrease in blood flow inside the liver and may lead to liver damage. Signs and symptoms include weight gain, yellowing of the skin and whites of the eyes, dark-colored urine, and increased liver size. It may occur at some point in time after radiation therapy to the liver and bile ducts or after high-dose anticancer drugs were given before a stem cell transplant. Also called sinusoidal obstruction syndrome.

2012-06-13