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Cardiovascular disease causes more than half of all the deaths in the U.S. It afflicts people of all ages, robbing us of our precious newborns, our children, our parents and our grandparents.

University of Minnesota Heart Care and the University's Lillehei Heart Institute have made it their mission to change that. Their breakthrough research discoveries have changed the face of cardiovascular disease.

The Institute reflects the legacy of the University of Minnesota medical pioneers who created our ongoing culture of innovation and discovery. Today, established faculty researchers are working together with the next generation of young investigators to conduct research in all aspects of treatment and prevention, and lessen the toll of cardiovascular disease on all of us.

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Clinical Trials

Research and clinical trials are part of what defines academic medicine. Volunteer participation in studies at the University of Minnesota enables the medical breakthroughs that we are known for.

To learn about participating in clinical trials or to search for a specific study, visit the University of Minnesota Study Finder.

Study Finder

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Some recent innovations that have benefited our patients:

  • Discovered a set of genetic markers for heart attack or stroke, which can lead to earlier preventive efforts aimed at reducing the chance of cardiovascular problems
  • Discovered the master gene for blood vessel development, allowing targeting of the gene for future treatments for blood vessel disease
  • Developed a bioartificial organ and engineered a beating heart in the laboratory to aid in the development of future biomedical devices
  • Developed guardian angel technology to monitor heart activity and prevent recurring episodes of chronic disease like heart failure
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About the University of Minnesota Lillehei Heart Institute

The Institute is built on the legacy of University of Minnesota icons that created a culture of innovation and discovery. These professors, together with their students and staff, blazed the trail in heart surgery; pioneered new therapies in heart failure; established the link between cholesterol and arteriosclerosis; and set the stage for world-renowned programs in organ transplantation. Today, established investigators who have secured highly competitive federal, corporate and foundation research grants working together with the next generation of young investigators to lessen the toll of cardiovascular disease on all of us.

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