Stem cell scientist Meri Firpo uses several types of stem cells to improve understanding of human development and find ways to prevent and cure disease. She is perfecting ways to make new stem cell lines from embryonic and adult tissue. Firpo also is transforming stem cells into pancreatic cells in the laboratory. The pancreatic cells may be able to be used for transplantation as a future cure for diabetes. They also are used in studies that investigate how type 1 diabetes develops and how to fight the disease.
Abeyta MJ, Clark AT, Rodriguez RT, Bodnar MS, Pera RA, Firpo MT. Unique gene expression signatures of independently-derived human embryonic stem cell lines. Hum Mol Genet. 13(6):601-8. Epub 2004 Jan 28. (2004)
Bodnar M.S., Meneses J.J., Rodriguez R.R., Firpo M.T. Propagation and maintenance of undifferentiated human embryonic stem cells. Stem Cells and Development 13(3):243 (2004)
GM Beattie, Lopez AD, Bucay N, Hinton A, Firpo MT, King CC, Hayek A. Activin A maintains pluripotentiality of human embryonic stem cells in the absence of feeder layers. Stem Cells. 23(4):489-95 (2005)
R. Rodriguez, Velkey, M., Lutzko, C. Bodnar, M., Kohn, D., O’Shea, K.S., Firpo, M.T. (2007) Manipulation of OCT-4 levels in human embryonic stem cells results in induction of differential cells types.
Cornell University Medical College Graduate School of Medical Sciences
Doctor of philosophy - Cornell University Medical College Graduate School of Medical Sciences
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